One of the consequences of the CoVid-19 epidemic has greatly changed the ways of teaching in schools. It had a special effect on the teaching of subjects derived from the natural sciences, including the teaching of biology, which is based on the practical work of students through the study of natural specimens, phenomena and processes. In such changed conditions, the previous methods of learning and teaching had to change significantly, most often in the direction of reducing the previous forms of work. The aim of this research is to determine the quality of biology teaching in epidemiological conditions, which includes examining the satisfaction and motivation of teachers and students in the adapted ways of working, difficulties and advantages they encountered and suggestions for improving teaching in new circumstances. The survey was conducted through an online questionnaire during 2021 and 2022, and involved 352 students and 35 teachers from several primary schools in the wider area of the city of Split. The difficulties that students point out as the most common are mostly of a technical nature, such as poorer picture and sound quality, poor internet connection and the obsolescence of the devices used. As difficulties, teachers also point out the technical ones, but also the need for longer preparation for teaching, insufficient digital literacy, reduced control over the class and poor feedback on learning success. As suggestions for improving teaching in extraordinary conditions, most students did not have certain ideas, while some pointed out the need for more frequent interactions with the teacher in online learning, and less independent tasks. As suggestions, teachers pointed out the need for better mastery of digital tools, more frequent testing of knowledge, teaching in a way that will motivate students and avoiding block classes in the schedule.