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undergraduate thesis
Svojstva i karakteristike α-kobra toksina roda Naja
2022. urn:nbn:hr:166:414265
Matković, Nikolina
University of Split
Faculty of Science
Department of Chemistry

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Matković, N. (2022). Svojstva i karakteristike α-kobra toksina roda Naja (Undergraduate thesis). Split: University of Split, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:166:414265

Matković, Nikolina. "Svojstva i karakteristike α-kobra toksina roda Naja." Undergraduate thesis, University of Split, Faculty of Science, 2022. https://urn.nsk.hr/urn:nbn:hr:166:414265

Matković, Nikolina. "Svojstva i karakteristike α-kobra toksina roda Naja." Undergraduate thesis, University of Split, Faculty of Science, 2022. https://urn.nsk.hr/urn:nbn:hr:166:414265

Matković, N. (2022). 'Svojstva i karakteristike α-kobra toksina roda Naja', Undergraduate thesis, University of Split, Faculty of Science, accessed 29 November 2024, https://urn.nsk.hr/urn:nbn:hr:166:414265

Matković N. Svojstva i karakteristike α-kobra toksina roda Naja [Undergraduate thesis]. Split: University of Split, Faculty of Science; 2022 [cited 2024 November 29] Available at: https://urn.nsk.hr/urn:nbn:hr:166:414265

N. Matković, "Svojstva i karakteristike α-kobra toksina roda Naja", Undergraduate thesis, University of Split, Faculty of Science, Split, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:166:414265

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Metadata
TitleSvojstva i karakteristike α-kobra toksina roda Naja
Title (english)Properties and characteristics of α-cobra toxin in the genus Naja
AuthorNikolina Matković
MentorViljemka Bučević Popović (mentor)
MentorRoko Vladušić (pomoć pri izradi, neposredni voditelj)
Committee memberViljemka Bučević Popović (predsjednik povjerenstva)
Committee memberStjepan Orhanović (član povjerenstva)
Committee memberRoko Vladušić (član povjerenstva)
GranterUniversity of Split
Faculty of Science
(Department of Chemistry)
Split
Defense date and country2022-09-27, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
Zmijski otrov je izlučevina preoblikovanih žlijezda slinovnica. Sadrži dvadesetak tvari. Više od 90% suhog zmijskog otrova čine proteini. Neki od njih su toksični, a neki ne pokazuju toksična svojstva. Jedan od toksina je α-kobra toksin. α-Kobra toksin spada u α-neurotoksine s dugim lancem, a pronalazimo ga kod vrsta roda Naja. α-Kobra toksin antagonist je nikotinskog acetilkolinskog receptora (nAChR). Vezanjem na nAChR mišićnog i neuronskog tipa, blokira sposobnost receptora da veže acetilkolin. Na taj način inhibira protok iona kroz postsinaptičku membranu što dovodi do paralize i prestanka disanja. Kod ugriza otrovnica roda Naja najčešće se primjenjuju polivalentni protuotrovi.
Abstract (english)
Snake venom is an excretion of transformed salivary glands and contains about twenty substances. More than 90% of dry snake venom consist of proteins. Some of them are toxic and some do not show toxic properties. One of the toxins is α-cobra toxin. α-Cobra toxin belongs to α-neurotoxins with a long chain, and it is found in a species of the genus Naja. α-Cobra toxin is an antagonist of the nicotinic acetylcholine receptor (nAChR). By binding to muscle and neuronal type nAChR, it blocks the receptor's ability to bind acetylcholine. In this way it inhibits the flow of ions through the postsynaptic membrane, leading to paralysis and cessation of breathing. Polyvalent antivenoms are most often used in the case of bites by venomous snakes of the genus Naja.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:166:414265
Study programmeTitle: Biology and Chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije i kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije i kemije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2023-03-02 13:36:40