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undergraduate thesis
Primjena biljaka u proizvodnji rekombinantnih proteina i antitijela
2018. urn:nbn:hr:166:201348
Ćaleta, Anna
University of Split
Faculty of Science
Department of Biology

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Ćaleta, A. (2018). Primjena biljaka u proizvodnji rekombinantnih proteina i antitijela (Undergraduate thesis). Split: University of Split, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:166:201348

Ćaleta, Anna. "Primjena biljaka u proizvodnji rekombinantnih proteina i antitijela." Undergraduate thesis, University of Split, Faculty of Science, 2018. https://urn.nsk.hr/urn:nbn:hr:166:201348

Ćaleta, Anna. "Primjena biljaka u proizvodnji rekombinantnih proteina i antitijela." Undergraduate thesis, University of Split, Faculty of Science, 2018. https://urn.nsk.hr/urn:nbn:hr:166:201348

Ćaleta, A. (2018). 'Primjena biljaka u proizvodnji rekombinantnih proteina i antitijela', Undergraduate thesis, University of Split, Faculty of Science, accessed 11 December 2024, https://urn.nsk.hr/urn:nbn:hr:166:201348

Ćaleta A. Primjena biljaka u proizvodnji rekombinantnih proteina i antitijela [Undergraduate thesis]. Split: University of Split, Faculty of Science; 2018 [cited 2024 December 11] Available at: https://urn.nsk.hr/urn:nbn:hr:166:201348

A. Ćaleta, "Primjena biljaka u proizvodnji rekombinantnih proteina i antitijela", Undergraduate thesis, University of Split, Faculty of Science, Split, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:166:201348

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Metadata
TitlePrimjena biljaka u proizvodnji rekombinantnih proteina i antitijela
Title (english)Plant molecular pharming (PMP)
AuthorAnna Ćaleta
MentorIvica Šamanić (mentor)
Committee memberIvica Šamanić (predsjednik povjerenstva)
Committee memberAna Maravić (član povjerenstva)
Committee memberŽeljana Fredotović (član povjerenstva)
GranterUniversity of Split
Faculty of Science
(Department of Biology)
Split
Defense date and country2018-09-18, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Biljke se od davnina koriste za liječenje raznih bolesti. Osim klasičnih načina sinteze lijekova pomoću bakterija, kvasaca i uzgoja u kulturi životinjskih stanica, u današnje vrijeme se razmatra i mogućnost uzgoja genetski modificiranih biljaka koje sadrže rekombinantne proteine i antitijela za borbu protiv različitih patogena. Ti vrijedni sastojci se zatim mogu ekstrahirati i primijeniti u imunizaciji ili se može pojesti sami plod biljke te tada govorimo o ˝jestivom cjepivu˝. Najpoznatiji primjer lijeka proizvedenog u biljci je ZMapp, a koristio se 2014. godine protiv virusa ebole. ˝Jestiva cjepiva˝ još nisu primijenjena na ljudima, razvijaju se postepeno, dok su samo neka testirana na životinjama. Tehnologija proizvodnje farmaceutskih transgeničnih biljaka susreće se s brojnim prednostima i nedostacima te razrađuje posebne protokole za pojedinu biljnu vrstu. Koncept hrane, kao sredstva za imunizaciju, potencijalno bi mogao riješiti problem epidemija i zaraznih bolesti u siromašnim zemljama, čiji stanovnici nemaju pristup adekvatnoj medicinskoj skrbi.
Abstract (english)
Since earliest times, plants have been used to treat diseases. In additional to traditional methods of drug discovery using bacteria, yeast and cultured animal cells, plants which has been genetically engineered to contain recombinant proteins and antigens for vaccine development are being considered. These ingredients are taken out and can be used for immunization or also antigens produced in edible parts of the plants can be administered orally. Experimental drug ZMapp is produced in genetically modified tobacco plants which was first used on humans during the 2014 as a treatment for Ebola virus disease. ˝Edible vaccines¨ must be tested thoroughly on animals and then on humans to validate their efficacy. Plant pharming is faced with the numerous benefits and disadvantages in the production of edible vaccines of transgenic plants and elaborates special protocols for a particular plant species. The idea of plant derived edible vaccines have a possibility of preventing the spread of the infectious disease in poor countries with very poor health system.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:166:201348
Study programmeTitle: Nutrition
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) nutricionizma)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2018-10-29 15:59:04