In this work we tried to show the evaluation of aesthetic characteristics of the web interface and the way it affects to interaction between humans and computers. This influence can be good or bad. The conclusion of this research is that the aesthetics and a web interface are closely related because it always starts from the thesis that the users like those web user interfaces that are "more beautiful and easy on the eyes." One of the most important concepts in today's information technology is a web interface that has to be in the center of the development of human-computer interaction. Human-computer interaction is scientific discipline that deals with the planning and design of the interaction between human and machine (personal computer, mobile phone, etc.). This discipline is the intersection of many scientific and applied scientific disciplines: computer science, design, psychology, art. The interaction between human and machine takes place usually through an interface. Emphasis in the application of web interface has a visual aesthetics, but in general aesthetics. The aesthetics as a single discipline, except in literature and art, has found its place in computer technology. There is a direct and classic aesthetics. The visual aesthetics is only one aspect of the interaction of aesthetics in information technology. The visual aesthetics usually refers to a pleasant appearance of objects or designed items that are based on computer technology. A special emphasis is given to three aspects relating to the design perspectives, psychological perspective and practical perspective. One of the most important questions about getting the web interfaces with the humans is their way of processing and evaluating the visual stimuli. In addition to evaluating the web interfaces, particular emphasis is given to the usability of web interfaces. The usability of web interfaces can be defined as a qualitative characteristic that determines how much is simple to use web interface.