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undergraduate thesis
Molekularna biologija i genetika cistične fibroze
2023. urn:nbn:hr:166:197985
Anadolac, Alisa
University of Split
Faculty of Science
Department of Biology

Cite this document

Anadolac, A. (2023). Molekularna biologija i genetika cistične fibroze (Undergraduate thesis). Split: University of Split, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:166:197985

Anadolac, Alisa. "Molekularna biologija i genetika cistične fibroze." Undergraduate thesis, University of Split, Faculty of Science, 2023. https://urn.nsk.hr/urn:nbn:hr:166:197985

Anadolac, Alisa. "Molekularna biologija i genetika cistične fibroze." Undergraduate thesis, University of Split, Faculty of Science, 2023. https://urn.nsk.hr/urn:nbn:hr:166:197985

Anadolac, A. (2023). 'Molekularna biologija i genetika cistične fibroze', Undergraduate thesis, University of Split, Faculty of Science, accessed 15 April 2024, https://urn.nsk.hr/urn:nbn:hr:166:197985

Anadolac A. Molekularna biologija i genetika cistične fibroze [Undergraduate thesis]. Split: University of Split, Faculty of Science; 2023 [cited 2024 April 15] Available at: https://urn.nsk.hr/urn:nbn:hr:166:197985

A. Anadolac, "Molekularna biologija i genetika cistične fibroze", Undergraduate thesis, University of Split, Faculty of Science, Split, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:166:197985

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Metadata
TitleMolekularna biologija i genetika cistične fibroze
Title (english)Molecular biology and genetics of cystic fibrosis
AuthorAlisa Anadolac
MentorJasna Puizina (mentor)
Committee memberJasna Puizina (predsjednik povjerenstva)
Committee memberSanja Puljas (član povjerenstva)
Committee memberŽeljana Fredotović (član povjerenstva)
GranterUniversity of Split
Faculty of Science
(Department of Biology)
Split
Defense date and country2023-09-13, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Cistična fibroza je genetska nasljedna bolest koja se nasljeđuje recesivno. Posljedica je mutiranog proteina CFTR, a klase mutacije i klinička slika obzirom na klase određuju se po ekspresiji, funkcionalnosti i strukturi mutiranog proteina. Protein CFTR važan je za aktivnost ionskih kanala kojima se prenose kloridni ioni. Nakupljanjem kloridnih iona uslijed mutiranog proteina CFTR stvara se gusta mukozna sluz koja je jedna od glavnih karakteristika oboljelih s cističnom fibrozom. Bolest je do današnjeg dana letalna što znači da još uvijek nije pronađen djelotvoran lijek koji suzbija bolest, ali se radi na istraživanju djelotvornih agenasa koji bi suzbili mutacije na proteinu CFTR i potakli na sintezu ispravnih.
Abstract (english)
Cystic fibrosis is a genetic hereditary disease that is inherited recessively. It is the result of a mutated CFTR protein and the mutation class and the clinical picture according to the class are determined by the expression, functionality and structure of the mutated protein. CFTR protein is important for the activity of ion channels that transport chloride ions. Due to the accumulation of chloride ions due to the mutated CFTR protein, thick mucous mucus is created, which is one of the main characteristics of patients with cystic fibrosis. To this day, the disease is lethal, which means that an effective drug that suppresses the disease has not been found, but research is being done on effective agents that would suppress mutations on the CFTR protein and stimulate the synthesis of correct ones.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:166:197985
Study programmeTitle: Biology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2023-09-18 12:48:55