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undergraduate thesis
Utjecaj bisfenola A na zdravlje
2017. urn:nbn:hr:166:688029
Karamarko, Ivan
University of Split
Faculty of Science
Department of Chemistry

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Karamarko, I. (2017). Utjecaj bisfenola A na zdravlje (Undergraduate thesis). Split: University of Split, Faculty of Science. Retrieved from https://urn.nsk.hr/urn:nbn:hr:166:688029

Karamarko, Ivan. "Utjecaj bisfenola A na zdravlje." Undergraduate thesis, University of Split, Faculty of Science, 2017. https://urn.nsk.hr/urn:nbn:hr:166:688029

Karamarko, Ivan. "Utjecaj bisfenola A na zdravlje." Undergraduate thesis, University of Split, Faculty of Science, 2017. https://urn.nsk.hr/urn:nbn:hr:166:688029

Karamarko, I. (2017). 'Utjecaj bisfenola A na zdravlje', Undergraduate thesis, University of Split, Faculty of Science, accessed 27 December 2024, https://urn.nsk.hr/urn:nbn:hr:166:688029

Karamarko I. Utjecaj bisfenola A na zdravlje [Undergraduate thesis]. Split: University of Split, Faculty of Science; 2017 [cited 2024 December 27] Available at: https://urn.nsk.hr/urn:nbn:hr:166:688029

I. Karamarko, "Utjecaj bisfenola A na zdravlje", Undergraduate thesis, University of Split, Faculty of Science, Split, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:166:688029

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Metadata
TitleUtjecaj bisfenola A na zdravlje
Title (english)The Effect of Bisphenol A on Health
AuthorIvan Karamarko
MentorStjepan Orhanović (mentor)
Committee memberStjepan Orhanović (predsjednik povjerenstva)
Committee memberIvana Anđelić (član povjerenstva)
Committee memberLinda Bazina (član povjerenstva)
GranterUniversity of Split
Faculty of Science
(Department of Chemistry)
Split
Defense date and country2017-09-25, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Chemistry
Abstract
BPA je kemikalija koja se koristi u proizvodnji polikarbonatne plastike i epoksidnih smola. Njihova široka upotreba i sposobnost BPA da migrira iz njih uzrok su zašto je BPA toliko raširen i prisutan u okolišu. U ljudskom tijelu glavni metabolički put za eliminaciju BPA je glukouronizacija, dok je manje bitan put sulfatizacija. Većinu metabolita BPA koji nastaju uz citokrom P450 karakterizira jača estrogena aktivnost. Jedan metabolit MBP ima 1000 puta veću estrogenu aktivnost. BPA djeluje preko hormonskih receptora, G-protein spregnutog receptora i djelujući direktno na DNK. BPA je endokrini disruptor, štetno utječe na reprodukciju. Pronađena je veza s pojavom metaboličkih bolesti, ima ulogu u kancerogenezi. Ometa funkcioniranje gušterače i slabi imunitet.
Abstract (english)
Bisphenol A is a chemical used in the production of polycarbonate plastic and epoxy resin. Their widespread use and the ability of BPA to migrate is the reason why BPA is so common in our environment. In the human body, the main metabolic pathway for elimination of BPA is glucouronidation, while sulfatation is the less important. Most BPA metabolites formed at presence of cytochrome P450 have higher estrogenic activity. One metabolite, MBP has 1000 times greater estrogenic activity. BPA binds with hormone receptors, G-protein coupled receptors and acts on DNA directly. BPA is an endocrine disruptor, it adversely affects reproduction. It is linked with the occurrence of metabolic diseases, it has a role in cancerogenesis. BPA impairs function of pancreas and weakens immunity.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:166:688029
Study programmeTitle: Biology and Chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije i kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije i kemije)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2018-01-31 15:56:18