Tissue engineering together with regenerative medicine (the joint name TERM) has experienced great development in the past decades, stimulated by the insufficient number of organ donors and immunological rejection of transplants. The combination that brings the greatest success in engineering is the alignment of three elements, namely scaffolds, cells and the necessary biosignals for tissue development in the laboratory. It is important to use a good technique, and this paper describes four frequently applied techniques. After the successful skin graft, many thought that in a few years they would be able to grow organs in a dish, but that did not happen. They encountered numerous problems, from insufficient development of scaffolds, few sources and difficult control of differentiation of stem cells, insufficient tissue blood supply, immune rejection of transplants, lack of knowledge of proteins, genes, polysaccharides and so on. Although clinical applications have not been so successful so far, scientists hope that the future will be brighter by researching new techniques and applying new knowledge from the field of science.