Usporedba citotoksične aktivnosti hidrolata pripremljenog iz vrste Dittrichia viscosa (L.) Greuter sakupljene 2017. i 2021. godine

Kokotović, Iva

prikaz prve stranice dokumenta Usporedba citotoksične aktivnosti hidrolata pripremljenog iz vrste Dittrichia viscosa (L.) Greuter sakupljene 2017. i 2021. godine

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master's thesis

Usporedba citotoksične aktivnosti hidrolata pripremljenog iz vrste Dittrichia viscosa (L.) Greuter sakupljene 2017. i 2021. godine

2021. urn:nbn:hr:166:987166

Kokotović, Iva

University of Split
University of Split, Faculty of science
Department of Biology

Cite this document

APA 6th Edition

Kokotović, I. (2021). Usporedba citotoksične aktivnosti hidrolata pripremljenog iz vrste Dittrichia viscosa (L.) Greuter sakupljene 2017. i 2021. godine (Master's thesis). Retrieved from https://urn.nsk.hr/urn:nbn:hr:166:987166

MLA 8th Edition

Kokotović, Iva. "Usporedba citotoksične aktivnosti hidrolata pripremljenog iz vrste Dittrichia viscosa (L.) Greuter sakupljene 2017. i 2021. godine." Master's thesis, University of Split, University of Split, Faculty of science, 2021. https://urn.nsk.hr/urn:nbn:hr:166:987166

Chicago 17th Edition

Harvard

Kokotović, I. (2021). 'Usporedba citotoksične aktivnosti hidrolata pripremljenog iz vrste Dittrichia viscosa (L.) Greuter sakupljene 2017. i 2021. godine', Master's thesis, University of Split, University of Split, Faculty of science, accessed 29 May 2022, https://urn.nsk.hr/urn:nbn:hr:166:987166

Vancouver

Kokotović I. Usporedba citotoksične aktivnosti hidrolata pripremljenog iz vrste Dittrichia viscosa (L.) Greuter sakupljene 2017. i 2021. godine [Master's thesis]. Split: University of Split, University of Split, Faculty of science; 2021 [cited 2022 May 29] Available at: https://urn.nsk.hr/urn:nbn:hr:166:987166

IEEE

I. Kokotović, "Usporedba citotoksične aktivnosti hidrolata pripremljenog iz vrste Dittrichia viscosa (L.) Greuter sakupljene 2017. i 2021. godine", Master's thesis, University of Split, University of Split, Faculty of science, Split, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:166:987166

Cite this item: https://urn.nsk.hr/urn:nbn:hr:166:987166

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Metadata

Title	Usporedba citotoksične aktivnosti hidrolata pripremljenog iz vrste Dittrichia viscosa (L.) Greuter sakupljene 2017. i 2021. godine
Title (english)	Comparison of cytotoxic activity of hydrosol prepared from Dittrichia viscosa (L.) Greuter collected in 2017 and 2021
Author	Iva Kokotović
Mentor	Željana Fredotović (mentor)
Committee member	Željana Fredotović (predsjednik povjerenstva)
Committee member	Elma Vuko (član povjerenstva)
Committee member	Mirko Ruščić (član povjerenstva)
Granter	University of Split University of Split, Faculty of science (Department of Biology) Split
Defense date and country	2021-09-29, Croatia
Scientific / art field, discipline and subdiscipline	NATURAL SCIENCES Biology
Abstract	Dittrichia viscosa (L.) Greuter (Asteraceae) aromatična je biljna vrsta koja se od davnina koristi u narodnoj medicini. U ovom radu uspoređen je citotoksični učinak hidrolata ekstrahiranog iz osušenog biljnog materijala vodenom destilacijom 2017. i 2021. godine. Cilj je utvrditi utječe li dulji vremenski period čuvanja hidrolata na stabilnost ove biološke aktivnosti. Citotoksični učinak određen je MTS metodom na humanim staničnim linijama raka grlića maternice (HeLa), osteosarkoma (U2OS) i karcinoma debelog crijeva (HCT116). Kod HeLa i U2OS staničnih linija utvrđeno je da ne postoji statistički značajna razlika u citotoksičnom učinku hidrolata iz 2017. i 2021. godine. Stabilnost hidrolata je očuvana i navedeni vremenski period skladištenja hidrolata ne utječe na citotoksičnu aktivnost.
Abstract (english)	Dittrichia viscosa (L.) Greuter (Asteraceae) is an aromatic plant that has been used in folk medicine since ancient times due to its properties. In this paper, the cytotoxic effect of hydrosols extracted from dried plant material by water distillation in 2017 and 2021 was compared. The aim is to determine whether a longer period of hydrosol storage affects the stability of this biological activity. MTS method was used to determine cytotoxic effect on human cervical cancer (HeLa), osteosarcoma (U2OS) and colon cancer (HCT116) cell lines. Statistical analysis (ANOVA test) showed that there is no statistically significant difference in cytotoxic effect between the hydrosol prepared in 2017 and 2021 on HeLa and U2OS cell lines. For the HCT116 cell line, a statistically significant difference in cytotoxic activity was found between the two tested hydrosols. Based on results we can conclude that long-term storage of hydrosol does not affect its cytotoxic activity.
Keywords
Keywords (english)
Language	croatian
URN:NBN	urn:nbn:hr:166:987166
Study programme	Title: Biology and Chemistry; specializations in: major in teaching Course: major in teaching Study programme type: university Study level: graduate Academic / professional title: magistar/magistra edukacije biologije i kemije (magistar/magistra edukacije biologije i kemije)
Type of resource	Text
File origin	Born digital
Access conditions	Access restricted to students and staff of home institution
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Created on	2021-10-15 13:21:46