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undergraduate thesis
Stanična i molekularna biologija tumora
2021. urn:nbn:hr:166:757107
Litrić, Magdalena
University of Split
University of Split, Faculty of science
Department of Biology

Cite this document

Litrić, M. (2021). Stanična i molekularna biologija tumora (Undergraduate thesis). Retrieved from https://urn.nsk.hr/urn:nbn:hr:166:757107

Litrić, Magdalena. "Stanična i molekularna biologija tumora." Undergraduate thesis, University of Split, University of Split, Faculty of science, 2021. https://urn.nsk.hr/urn:nbn:hr:166:757107

Litrić, Magdalena. "Stanična i molekularna biologija tumora." Undergraduate thesis, University of Split, University of Split, Faculty of science, 2021. https://urn.nsk.hr/urn:nbn:hr:166:757107

Litrić, M. (2021). 'Stanična i molekularna biologija tumora', Undergraduate thesis, University of Split, University of Split, Faculty of science, accessed 27 May 2022, https://urn.nsk.hr/urn:nbn:hr:166:757107

Litrić M. Stanična i molekularna biologija tumora [Undergraduate thesis]. Split: University of Split, University of Split, Faculty of science; 2021 [cited 2022 May 27] Available at: https://urn.nsk.hr/urn:nbn:hr:166:757107

M. Litrić, "Stanična i molekularna biologija tumora", Undergraduate thesis, University of Split, University of Split, Faculty of science, Split, 2021. Available at: https://urn.nsk.hr/urn:nbn:hr:166:757107

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Metadata
TitleStanična i molekularna biologija tumora
Title (english)Cell and molecural biology of tumors
AuthorMagdalena Litrić
MentorŽeljana Fredotović (mentor)
Committee memberŽeljana Fredotović (predsjednik povjerenstva)
Committee memberElma Vuko (član povjerenstva)
Committee memberIvica Šamanić (član povjerenstva)
GranterUniversity of Split
University of Split, Faculty of science
(Department of Biology)
Split
Defense date and country2021-09-22, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Svaki organizam ima regulacijske mehanizme koji kontroliraju proliferaciju, diferencijaciju i preživljavanje stanice. Razni faktori poput kemijskih karcinogena, UV zračenja, hormona, virusa i bakterija negativno utječu na regulacijske mehanizme što uglavnom dovodi do razvoja stanica malignog karaktera. U kulturi tumorskih stanica vidljiv je neprekidan rast stanica koji je posljedica njihove sposobnosti samostalne produkcije faktora rasta. Karcinogeneza je složen proces u kojem važnu ulogu igraju onkogeni te tumor-supresorski geni. Onkogeni nastaju iz protoonkogena mutacijskog aktivacijom, dok tumor-supresori svojom inaktivacijom ili gubitkom funkcije vode razvoju zloćudnih tumora. Kod tumora se uočava neregulirana kontrola staničnog ciklusa pri čemu izbjegavaju kontrolna mjesta tzv. „checkpoints“ koja zaustavljaju proliferaciju u prisutnosti oštećene DNA. Cilj ovog završnog rada je opisati vrste tumora, objasniti njihov razvoj i svojstva, različite uzroke te gene povezane s njihovim nastankom. Poseban je naglasak stavljen na različite pristupe pri liječenju i prevenciji tumora.
Abstract (english)
Every organism has regulatory mechanisms that control cell proliferation, differentiation, and survival. Various factors such as chemical carcinogens, UV radiation, hormones, viruses and bacteria have a negative effect on the regulatory mechanisms, leading mainly to the development of malignant cells. In tumor cell cultures, continuous growth of cells can be observed as they are able to produce growth factors independently. Carcinogenesis is a complex process in which oncogenes and tumor suppressor genes play an important role. Oncogenes arise from protooncogenes through mutational activation, whereas tumor suppressors lead to the development of malignant tumors through their inactivation or loss of function. In tumors, unregulated control of the cell cycle is observed, with checkpoints that stop proliferation in the presence of damaged DNA. The aim of this thesis is to describe the types of tumors, explain their development and characteristics, various causes and genes associated with their development. Special emphasis is given to the different approaches for the treatment and prevention of tumors.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:166:757107
Study programmeTitle: Biology and Chemistry
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije i kemije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije i kemije)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2021-10-07 09:08:27